Cd86 Rat Monoclonal Antibody [Clone ID: 2D10]

CAT#: AM08084PU-N

Cd86 rat monoclonal antibody, clone 2D10, Purified

Conjugation: Unconjugated APC Biotin FITC PE



Need it in bulk or conjugated?
Get a free quote

CNY 4,136.00


货期*
4周

规格
    • 500 ug

Product images

Specifications

Product Data
Clone Name 2D10
Applications FC, FN, IHC, IP
Recommend Dilution ELISA. (Ref.4)
Flow Cytometry:
Identification and enumeration of CD86+ cells. (Ref.1,2,4,6,7)
Immunoprecipitation (Ref.1)
Immunohistochemistry on Frozen Sections: Identification of CD86+ cells. (Ref.4).
In vivo and in vitro blocking assays. (Ref.1-3,5)
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen Mouse B cell lymphoma cell line 5C2.
Specificity This antibody recognises CD86, the B7-2 costimulatory molecule and a ligand for CD28 and CD152.
Formulation 100 mM Borate Buffered Saline, pH 8.2.
No preservatives or amine-containing buffer salts added.
State: Purified
State: Liquid purified Ig fraction.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name CD86 antigen
Background CD86, also known as B72, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease. CD86 interacts with HHV8 (KSHV) MIR2 protein.
Synonyms CD28LG2, Activation B7-2 antigen, B70, BU63, B7.2, FUN-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...