INPP5F (OCRL) (NM_000276) Human Mass Spec Standard

CAT#: PH320672

OCRL MS Standard C13 and N15-labeled recombinant protein (NP_000267)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description OCRL MS Standard C13 and N15-labeled recombinant protein (NP_000267)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220672
Predicted MW 104 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_000267
RefSeq Size 5165
RefSeq ORF 2703
Synonyms Dent-2; DENT2; INPP5F; LOCR; NPHL2; OCRL-1; OCRL1
Locus ID 4952
Cytogenetics Xq26.1
Summary This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Protein Families Druggable Genome
Protein Pathways Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system
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