AASDHPPT (NM_015423) Human Mass Spec Standard

Specifications

Product Data
Description	AASDHPPT MS Standard C13 and N15-labeled recombinant protein (NP_056238)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205091
Predicted MW	35.8 kDa
Protein Sequence	Sequence Link (showhide) >RC205091 protein sequence Red=Cloning site Green=Tags(s) MVFPAKRFCLVPSMEGVRWAFSCGTWLPSRAEWLLAVRSIQPEEKERIGQFVFARDAKAAMAGRLMIRKL VAEKLNIPWNHIRLQRTAKGKPVLAKDSSNPYPNFNFNISHQGDYAVLAAEPELQVGIDIMKTSFPGRGS IPEFFHIMKRKFTNKEWETIRSFKDEWTQLDMFYRNWALKESFIKAIGVGLGFELQRLEFDLSPLNLDIG QVYKETRLFLDGEEEKEWAFEESKIDEHHFVAVALRKPDGSRHQDVPSQDDSKPTQRQFTILNFNDLMSS AVPMTPEDPSFWDCFCFTEEIPIRNGTKS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_056238
RefSeq Size	2880
RefSeq ORF	927
Synonyms	AASD-PPT; ACPS; CGI-80; LYS2; LYS5
Locus ID	60496
Cytogenetics	11q22.3
Summary	The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008]
Protein Pathways	Lysine biosynthesis, Lysine degradation, Metabolic pathways

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