Ubiquitin D (UBD) (NM_006398) Human Mass Spec Standard

Specifications

Product Data
Description	UBD MS Standard C13 and N15-labeled recombinant protein (NP_006389)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204431
Predicted MW	18.5 kDa
Protein Sequence	Sequence Link (showhide) >RC204431 protein sequence Red=Cloning site Green=Tags(s) MAPNASCLCVHVRSEEWDLMTFDANPYDSVKKIKEHVRSKTKVPVQDQVLLLGSKILKPRRSLSSYGIDK EKTIHLTLKVVKPSDEELPLFLVESGDEAKRHLLQVRRSSSVAQVKAMIETKTGIIPETQIVTCNGKRLE DGKMMADYGIRKGNLLFLACYCIGG TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006389
RefSeq Size	1006
RefSeq ORF	495
Synonyms	FAT10; GABBR1; UBD-3
Locus ID	10537
Cytogenetics	6p22.1
Summary	This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types. [provided by RefSeq, Aug 2017]
Protein Families	Druggable Genome

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