VASP (NM_003370) Human Mass Spec Standard

CAT#: PH303544

VASP MS Standard C13 and N15-labeled recombinant protein (NP_003361)



  View other "VASP" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of vasodilator-stimulated phosphoprotein (VASP)
    • 100 ug

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VASP mouse monoclonal antibody, clone OTI4D6 (formerly 4D6)
    • 100 ul

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Specifications

Product Data
Description VASP MS Standard C13 and N15-labeled recombinant protein (NP_003361)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203544
Predicted MW 40.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003361
RefSeq Size 2298
RefSeq ORF 1140
Locus ID 7408
Cytogenetics 19q13.32
Summary Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration
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